Too-low Diastolic Blood Pressure can be Deadly for CKD Patients: Study
But not all hope for vitamin D may be lost, said Dr. Edward Giovannucci, who wrote a commentary accompanying the new study in JAMA Internal Medicine. He told Reuters Health in an email that participants still had relatively high levels of vitamin D at the beginning of the study, which would decrease the chance of seeing a benefit from supplements. “Thus, the potential benefit of vitamin D on blood pressure could depend on one’s starting point,” Giovannucci, a professor of nutrition and epidemiology from the Harvard School of Public Health in Boston, said.
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For CKD Patients too-low Diastolic Blood Pressure Can be Deadly.br> Having too-low diastolic blood pressure (DBP) may be deadly for patients with chronic kidney disease (CKD). Blood pressure (BP) recommendations are stricter for patients with CKD than for the general population and focus on lowering actual BP (the measurement of both systolic BP [SBP] and DBP) without consideration for achieving a DBP that is too low. Researchers reviewed health records for 651,749 U.S. veterans with CKD to assess the association between BP and death. Both actual BP and measurements of SBP and DBP considered separately were assessed. The researchers found that having a systolic blood pressure of 130 to 159 mm Hg and diastolic blood pressure of 70 to 89 mm Hg was associated with the lowest risk for death.
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Low Blood Pressure Linked to Death Risk, Study Finds
Researcher Csaba Kovesdy, MD, and others at the Memphis Veterans Affairs Medical Center in Tennessee looked at more than 18 million blood pressure measurements and found that for patients with either very high or very low blood pressure, mortality went up substantially. Relative risk of mortality was significantly increased, by more than five times, according to the study, published today in the Annals of Internal Medicine. The researchers found that blood pressures in the range of 130 to 159 mm HG systolic over 70 to 89 diastolic were associated with the best health outcomes for the population they studied men with kidney disease. Dena Rifkin, MD, suggested that the new study may not yet apply to the general population, but only to this large group of older veterans with chronic kidney disease . Dr. Rifkin is from the Veterans Affairs Healthcare System in San Diego, California.
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